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Cagrilintide (Amylin Analogue) | 5mg Research Grade

Cagrilintide (Amylin Analogue) | 5mg Research Grade

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Cagrilintide 5mg is a synthetic, long-acting acylated Amylin analogue engineered for the study of complex metabolic signaling pathways. In laboratory environments, this compound serves as a non-selective agonist for both the Amylin receptor (AMYR) and the Calcitonin G protein-coupled receptor (CTR).

While first-generation metabolic research focused predominantly on incretin-mimetic (GLP-1) pathways, Cagrilintide provides a high-affinity tool for investigating the interaction between amylin-linked signaling and homeostatic regulation within in vitro and experimental models.


Primary Areas of Laboratory Interest

1. Multi-Receptor Signaling & Crosstalk

Unlike single-pathway analogues, Cagrilintide interacts with the amylin and calcitonin receptors. This enables researchers to investigate:

  • Combinatorial Agonism: Studying the synergistic effects of simultaneous receptor activation.

  • Systemic Crosstalk: Analyzing the communication between disparate metabolic signaling systems and their influence on energy homeostasis.

2. Gastric Motility & Nutrient Signaling

Research focuses on the compound’s ability to modulate gastrointestinal kinetics:

  • Kinetic Modeling: Observing changes in gastric emptying rates within laboratory models.

  • Nutrient intake Signaling: Studying the biochemical markers associated with nutrient passage and satiety-linked triggers in experimental frameworks.

3. Acylated Stability & Persistence

The molecule features a C20 fatty diacid side chain, a structural modification that facilitates long-term study:

  • Extended Half-Life: This acylation results in a prolonged half-life (approximately 160 hours).

  • Longitudinal Research: The increased stability allows for consistent steady-state observations in chronic research models without frequent re-administration.

4. Neuro-Metabolic Feedback Loops

Cagrilintide is a primary subject in studies regarding the central nervous system’s role in metabolic regulation:

  • Homeostatic Reward Pathways: Investigating the modulation of reward-pathway triggers within the hindbrain and hypothalamus.

  • Metabolic Feedback: Studying the integration of peripheral hormone signals and their impact on central metabolic control.

 

 

⚠️ RESEARCH DISCLOSURE: This product is strictly for laboratory research purposes only. It is not intended for human or animal consumption. By purchasing this product, you acknowledge its status as a research chemical and agree to follow all safety and handling protocols.

 

In Relation to Cartridge and Pen Orders

 The product is reconstituted with 3ml BAC on day of dispatch to maximise potency by the time it arrives. To keep costs minimal, we do not ship with cool packs the product should maintain potency at room temperature for up to 21 days, and should be stored refrigerated as soon as you receive. 

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Research Use Only (RUO) & Terms of Sale
1. Intended Use
All products sold by Midland Peptides are intended strictly for laboratory research purposes only. These products are not intended for human or animal consumption, diagnostic purposes, medical use, therapeutic application, or use as a food additive, drug, or cosmetic.

2. No Regulatory Approval
You acknowledge that the products offered on this website have not been evaluated or approved by the Food and Drug Administration (FDA) or any other regulatory body for any clinical or human use. These compounds are in the research phase of development and their safety and efficacy profiles have not been established.

3. Restriction on Human Administration
By purchasing from this site, the buyer agrees that:

Under no circumstances shall these products be introduced into a human or animal body via injection, ingestion, or any other method.

Any communication—via email, chat, or phone—requesting dosing information, reconstitution protocols for human use, or medical advice will result in the immediate termination of the customer’s account and the cancellation of all pending orders.

4. Buyer Responsibility & Compliance
The purchaser assumes all responsibility for the safe handling, storage, and use of these materials. The buyer warrants that they are:

At least 18 years of age (or the age of majority in their jurisdiction).

Affiliated with a legitimate research institution or possess the technical skills required to handle research chemicals.

In compliance with all local, state, and federal laws regarding the purchase and possession of research peptides.

5. Limitation of Liability
[Your Company Name] shall not be held liable for any damages—including but not limited to personal injury, health complications, or legal consequences—arising from the misuse, accidental ingestion, or unauthorized application of these products. All products are provided "AS IS" without any express or implied warranties of fitness for a particular purpose.

Zero Tolerance Policy
We maintain a strict zero-tolerance policy regarding the misuse of our products. We do not provide "human use" protocols. If we suspect a product is being purchased for non-research purposes, we reserve the right to refuse service.